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[造血系统疾病和恶性淋巴瘤中的骨骼改变]

[Bone changes in hemoblastoses and malignant lymphomas].

作者信息

Stenzel L, Krug K, Franke J, Fengler F, Runge H, Petzold L, Sickel W

出版信息

Z Gesamte Inn Med. 1979 Jul 15;34(14):183-5.

PMID:538994
Abstract

In haematological systemic diseases such as acute and chronic leukoses, malignant lymphomas, lymphogranulomatoses, osteomyelofibroses, polycythaemias and aplastic anaemias with a different proportion changes of the bones in form of osteoporoses, osteolytic processes and deformations of the vertebral bodies are to be found. The proof may be performed radiologically and histologically. In 461 patients with different haematological diseases absorption measurings of monoenergetic rays of a J-125-source were performed at the distal third of radius and ulna. It was shown that the bone mineral content of patients with proved bone destructions did not significantly differ from the normal group. The too peripherally located place of the measuring and also the late inclusion of the compacta into the changes is regarded as cause for the negative result.

摘要

在血液系统全身性疾病中,如急慢性白血病、恶性淋巴瘤、淋巴肉芽肿病、骨髓纤维化、红细胞增多症和再生障碍性贫血,会出现不同比例的骨质疏松、骨质溶解过程以及椎体变形等骨骼形态变化。可通过放射学和组织学方法进行验证。对461例患有不同血液疾病的患者,在桡骨和尺骨远端三分之一处进行了J - 125源单能射线的吸收测量。结果表明,经证实有骨质破坏的患者的骨矿物质含量与正常组无显著差异。测量部位过于外周以及致密骨较晚才纳入病变范围被认为是导致阴性结果的原因。

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