Jellis J E, Muyangana J
Med J Zambia. 1979 Aug-Sep;13(4):72-4.
A single-blind trial of diflunisal (Dolobid) against osyphenbutazone (Tanderil) was performed in a randomised series of 50 patients undergoing various orthopaedic operations. The patients were screened for the known contra-indications to both drugs. All those admitted to the trial had considerable pain on the first post-operative morning. Diflunisal was found significantly more efficacious in the relief of orthopaedic post-operative pain. No significant side-effects were recorded for either drug.
在50例接受各种骨科手术的患者中进行了一项双氯芬酸(双氯灭痛)与羟布宗(坦德瑞)的单盲试验。对患者进行了这两种药物已知禁忌症的筛查。所有纳入试验的患者在术后第一个早晨都有相当程度的疼痛。结果发现双氯芬酸在缓解骨科术后疼痛方面明显更有效。两种药物均未记录到明显的副作用。