Lunow E, Müller M
Zentralbl Gynakol. 1979;101(20):1314-22.
Reported in this paper is experience so far obtained from graduated or stepwise treatment of carcinoma in situ. The report is based on the author's own experience obtained from 716 cases as well as on another 342 carcinomas in situ which had been evaluated earlier and elsewhere by Mosler and co-workers. The five-year healing rate accounted for 99.87 per cent. The first and second periods of follow-up checks were compared for all 1,058 in situ carcinoma cases under review, and the following conclusion were drawn: 1. More women were involved in prophylactic gynaecological checks. - 2. The age peak of carcinoma in situ cases in the second follow-up period was two years below that observed in the first period. - 3. Decline in cases with carcinoma location in ectocervix only, but increase in cases with carcinomas in situ of endocervical or endocervical together with ectocervical locations. - The following advantages are likely to be obtainable from conisation over general use of simple hysterectomy and even more over radical surgery, provided observance of the conditions specified in this paper: 1 Mitigation of physical and psychic surgical trauma and its consequences; - 2. Less exposure to severe potential intra-operative and/or postoperative complications; - 3. Savings on cost of treatment resulting from shorter hospitalisation and reduced need for nursing, medicaments, and attention, using hardware.
本文报道了目前从原位癌的分级或逐步治疗中获得的经验。该报告基于作者自身从716例病例中获得的经验,以及莫斯勒及其同事先前在其他地方评估的另外342例原位癌病例。五年治愈率为99.87%。对所有1058例接受审查的原位癌病例的第一和第二次随访检查进行了比较,得出以下结论:1. 参与预防性妇科检查的女性更多。- 2. 第二次随访期原位癌病例的年龄高峰比第一次观察到的低两岁。- 3. 仅宫颈外口原位癌病例减少,但宫颈内原位癌或宫颈内与宫颈外原位癌病例增加。- 如果遵守本文规定的条件,与单纯子宫切除术的普遍使用相比,甚至与根治性手术相比,锥形切除术可能具有以下优点:1. 减轻手术对身体和心理的创伤及其后果;- 2. 较少暴露于严重的术中及/或术后潜在并发症;- 3. 通过缩短住院时间、减少护理、药物和使用硬件所需的护理,节省治疗费用。