Cukier J O, Maglalang A C, Odell G B
Acta Paediatr Scand. 1979 Nov;68(6):903-9. doi: 10.1111/j.1651-2227.1979.tb08231.x.
Littermate homozygous (jj) and heterozygous (Jj) Gunn rats, were irradiated with blue fluorescent light for 18 hours continuously. The incident irradiance was 1.5 mWatts/cm2 in the 420--480 nm band pass. The influence of the irradiance on circulating erthrocytes was studied by testing their osmotic fragility before and after the irradiance. The non-jaundiced, Jj, animals did not exhibit any increase in the osmotic fragility of their erythrocytes. The osmotic fragility of the erythrocytes from jaundiced, jj, animals was the same as the Jj animals prior irradiance. However, the fragility of the erythrocytes from the jj animals was significantly increased after the 18 hours of irradiance. The results indicated that the photodynamic action of bilirubin may be present in vivo.
同窝纯合子（jj）和杂合子（Jj）的冈恩大鼠连续18小时接受蓝色荧光照射。在420 - 480纳米带通范围内，入射辐照度为1.5毫瓦/平方厘米。通过检测辐照前后红细胞的渗透脆性，研究了辐照度对循环红细胞的影响。非黄疸的Jj动物红细胞的渗透脆性没有任何增加。黄疸的jj动物红细胞的渗透脆性在辐照前与Jj动物相同。然而，jj动物的红细胞在辐照18小时后脆性显著增加。结果表明胆红素的光动力作用可能存在于体内。
