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[通过实验模型分析血液和血浆粘度随流速的变化]

[Variations of hematic and plasmatic viscosity as a function of flow velocity, analyzed by means of an experimental model].

作者信息

Cortinovis A, Crippa A, Marchetti G, Belloni G, Pedroni G

出版信息

Chir Ital. 1979 Oct;31(5):926-45.

PMID:540387
Abstract

The authors have determined the hematic and plasmatic viscosity in 60 sound subjects, 30 men and 30 women respectively, at different values of cut drop, corresponding to the values that can be found at different levels of circulatory system. These subjects had value of Ht, total protidemy, cholesterolemy and trigliceryds, included in normal limits. For these determinations, made at constant temperature, they have used Well-Brookfield with a divergent angle of 0,8 degrees. In this way they could determinate the normality limits of hematic and plasmatic viscosity, in men and women, in connection with the physiologic modifications of flux speed. It has been confirmed the tixotropo behaviour of blood, whose viscosity increases exponentially for lessenings of cut drop and we have put this fact in touch with genesis of thrombosis. They haven't shown any expressive difference in the behaviour of the curves of two undergroups; the curve of middle values is higher for men, and it seems that this difference is owing to Ht. esclusively. In the end they have considered the curves of subjects that had values of viscosity different from normality; in this way they have found three different curves, in pathologic conditions.

摘要

作者测定了60名健康受试者(分别为30名男性和30名女性)在不同切变率下的血液和血浆粘度,这些切变率对应于在循环系统不同水平上可测得的值。这些受试者的血细胞比容、总蛋白、胆固醇和甘油三酯值均在正常范围内。为进行这些在恒定温度下的测定,他们使用了发散角为0.8度的Well-Brookfield仪器。通过这种方式,他们能够确定男性和女性血液和血浆粘度的正常范围,并与血流速度的生理变化相关联。已证实血液的触变性行为,即粘度随切变率降低呈指数增加,并且他们将这一事实与血栓形成的发生联系起来。他们未发现两个亚组曲线行为有任何显著差异;男性中间值曲线较高,且这种差异似乎仅归因于血细胞比容。最后,他们考虑了粘度值与正常情况不同的受试者的曲线;通过这种方式,他们在病理条件下发现了三种不同的曲线。

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