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原发性高血压患者急性应激期间的客观性能测量:普萘洛尔和美托洛尔的效果评估

Objective measurement of performance during acute stress in patients with essential hypertension: assessment of the effects of propranolol and metoprolol.

作者信息

Dunn F G, Lorimer A R, Lawrie T D

出版信息

Clin Sci (Lond). 1979 Dec;57 Suppl 5:413s-415s. doi: 10.1042/cs057413s.

Abstract
  1. A standardized method of objectively measuring performance during simulated car driving is described. 2. The effect of a single dose of propranolol and metoprolol were compared with placebo in two groups of patients with untreated essential hypertension. 3. Performance was similar after beta-adrenoreceptor-blocking agents or placebo. 4. Blood pressure response to stress persisted after administration of the blocking agents.
摘要
  1. 描述了一种在模拟汽车驾驶过程中客观测量表现的标准化方法。2. 在两组未经治疗的原发性高血压患者中,比较了单剂量普萘洛尔和美托洛尔与安慰剂的效果。3. 使用β-肾上腺素能受体阻滞剂或安慰剂后,表现相似。4. 服用阻滞剂后,血压对应激的反应仍然存在。

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