Scognamiglio F, Ramondo A, Congedo E, Stritoni P, Chioin R, Daliento L, Corbara F, Dalla Volta S
G Ital Cardiol. 1979;9(2):148-53.
60 patients with clinical signs of coronary artery disease who had a hemodynamic examination were studied. The study of the regional dynamics using the deformation as a vectorial time-dependent parameter and the pressure-length loops, was carried out on a total of 420 parietal regions of the left ventricle: the basal ventriculography, the post-extrasystolic potentiation and the ventriculography after nitroglycerin were evaluated. The dynamic regional pattern was correlated with clinical-enzimatic signs of necrosis in the electrocardiogram. The possibility of correlating signs of necrosis with particular patterns of hypokinesia, akinesia, dyskinesia which differ from corresponding "static" forms of asynergy in active pressure development and deformation (even in a brief systolic interval) seems to confirm the physiopathologic interpretation of the regional phenomenon based on the ratio between viable not viable myocardium -- as primary cause.
对60例有冠状动脉疾病临床症状且接受了血液动力学检查的患者进行了研究。使用变形作为随时间变化的矢量参数和压力-长度环对区域动力学进行研究，共对左心室的420个壁区域进行了研究：评估了基础心室造影、早搏后增强和硝酸甘油后的心室造影。动态区域模式与心电图中坏死的临床酶学体征相关。坏死体征与特定的运动减弱、运动不能、运动障碍模式相关的可能性，这些模式在主动压力发展和变形方面（即使在短暂的收缩期）不同于相应的“静态”协同失调形式，这似乎证实了基于存活心肌与非存活心肌比例作为主要原因的区域现象的病理生理学解释。
