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J Cell Biol. 1970 Jan;44(1):80-93. doi: 10.1083/jcb.44.1.80.
2
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Carotene in bovine milk fat globules: observations on origin and high content in tissue mitochondria.牛乳脂肪球中的胡萝卜素：关于其来源及在组织线粒体中高含量的观察
Lipids. 1980 Jan;15(1):33-8. doi: 10.1007/BF02534115.

本文引用的文献

1
A comparative study of the lipids of globule membrane and fat core and of the milk serum of cows.奶牛乳球膜、脂肪核及乳清脂质的比较研究。
Lipids. 1967 Nov;2(6):453-60. doi: 10.1007/BF02533171.
2
PURIFICATION OF PHOSPHOLIPIDS RECOVERED FROM THIN-LAYER CHROMATOGRAMS FOR INFRARED SPECTRAL ANALYSIS.
J Lipid Res. 1965 Apr;6:320-2.
3
STUDIES ON PLASMA MEMBRANES. I. CHEMICAL COMPOSITION AND ENZYME CONTENT OF PLASMA MEMBRANES ISOLATED FROM RAT LIVER.细胞膜研究。I. 从大鼠肝脏分离的细胞膜的化学组成和酶含量
Biochim Biophys Acta. 1964 Jul 15;90:126-45. doi: 10.1016/0304-4165(64)90125-4.
4
Electron microscopy of milk secretion in the mammary gland of the C3H/Crgl mouse. II. Identification of fat and protein particles in milk and in tissue.C3H/Crgl小鼠乳腺乳汁分泌的电子显微镜观察。II. 乳汁和组织中脂肪及蛋白质颗粒的鉴定。
J Natl Cancer Inst. 1960 Aug;25:423-37.
5
Electron microscopy of milk secretion in the mammary gland of the C3H/Crgl mouse. I. Cytomorphology of the prelactating and the lactating gland.C3H/Crgl小鼠乳腺乳汁分泌的电子显微镜观察。I. 泌乳前期和泌乳期腺体的细胞形态学。
J Natl Cancer Inst. 1960 Aug;25:393-421.
6
The isolation of a cell membrane fraction from rat liver.从大鼠肝脏中分离出细胞膜组分。
J Biophys Biochem Cytol. 1960 Oct;8(2):413-22. doi: 10.1083/jcb.8.2.413.
7
Fine structure of the cow's udder during gestation and lactation.奶牛乳房在妊娠期和泌乳期的精细结构。
Lab Invest. 1961 Mar-Apr;10:238-55.
8
The separation of complex lipide mixtures by the use of silicic acid chromatography.利用硅酸色谱法分离复杂脂质混合物。
J Biol Chem. 1958 Aug;233(2):311-20 20.
9
Determination of cerebrosides.脑苷脂的测定
J Biol Chem. 1955 Dec;217(2):789-96.
10
The lipoprotein particles in cow's milk.牛奶中的脂蛋白颗粒。
Biochem J. 1954 Jun;57(2):231-7. doi: 10.1042/bj0570231.

来自牛乳腺的质膜和乳脂肪球膜的生化与形态学比较

Biochemical and morphological comparison of plasma membrane and milk fat globule membrane from bovine mammary gland.

作者信息

Keenan T W, Morré D J, Olson D E, Yunghans W N, Patton S

出版信息

J Cell Biol. 1970 Jan;44(1):80-93. doi: 10.1083/jcb.44.1.80.

DOI:10.1083/jcb.44.1.80
PMID:5409465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2107778/
Abstract

Purified plasma membrane fractions from lactating bovine mammary glands and membranes of milk fat globules from the same source were similar in distribution and fatty acid composition of phospholipids. The sphingomyelin content of the phospholipid fraction of both membranes was higher than in these fractions from other cell components, beta-carotene, a constituent characteristic of milk fat, was present in the lipid fraction of the plasma membrane. Cholesterol esters of plasma membrane were similar in fatty acid composition to those of milk fat globule membranes. Disc electrophoresis of either membrane preparation on polyacrylamide gels revealed a single major protein component characteristic of plasma membrane from other sources. Distinct morphological differences between plasma membrane and milk fat globule membranes were observed in both thin sections and in negatively stained material. Plasma membrane was vesicular in appearance while milk fat globule membranes had a platelike aspect. These observations are consistent with derivation of fat globule membrane from plasma membrane accompanied by structural rearrangement of membrane constituents.

摘要

来自泌乳期奶牛乳腺的纯化质膜组分与同一来源的乳脂肪球膜在磷脂的分布和脂肪酸组成上相似。两种膜的磷脂组分中鞘磷脂含量均高于其他细胞成分的这些组分，β-胡萝卜素作为乳脂肪的一种特征成分，存在于质膜的脂质组分中。质膜的胆固醇酯在脂肪酸组成上与乳脂肪球膜的相似。在聚丙烯酰胺凝胶上对任一膜制剂进行圆盘电泳，均显示出一个来自其他来源的质膜特有的主要蛋白质成分。在超薄切片和负染材料中均观察到质膜与乳脂肪球膜之间明显的形态差异。质膜外观呈泡状，而乳脂肪球膜呈板状。这些观察结果与脂肪球膜源自质膜并伴有膜成分结构重排一致。