甲硝唑、硝唑与去氢依米丁联合治疗儿童阿米巴肝脓肿
Metronidazole and niridazole combined with dehydroemetine in treatment of children with amoebic liver abscess.
作者信息
Scragg J N, Powell S J
出版信息
Arch Dis Child. 1970 Apr;45(240):193-5. doi: 10.1136/adc.45.240.193.
Abstract
Metronidazole combined with dehydroemetine cured 13 of 15 children with amoebic liver abscess. An alternative combination of niridazole with dehydroemetine produced cure in 13 of 14 children. No relapses were observed. Electrocardiographic changes were noted in 2 of the first group and in 5 of those who received the second regimen. The results are similar to those obtained with emetine preparations combined with chloroquine. Either metronidazole or niridazole are effective substitutes for chloroquine and of these preparations metronidazole is preferred.
摘要
甲硝唑联合去氢吐根碱治疗15例阿米巴肝脓肿患儿，其中13例治愈。硝唑咪与去氢吐根碱的联合用药方案治疗14例患儿，13例治愈。未观察到复发情况。第一组中有2例出现心电图改变，接受第二种治疗方案的患儿中有5例出现心电图改变。结果与吐根碱制剂联合氯喹的治疗效果相似。甲硝唑或硝唑咪都是氯喹的有效替代药物，其中甲硝唑更受青睐。
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本文引用的文献
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Arch Dis Child. 1960 Apr;35(180):171-6. doi: 10.1136/adc.35.180.171.
2
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The cardiotoxicity of systemic amebicides. A comparative electrocardiographic study.全身用杀阿米巴药的心脏毒性。一项比较心电图研究。
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