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[Hypothetical metabolites of 2-bis(2-chloroethyl)amino-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide (cyclophosphamide)].

作者信息

Norpoth K, Golovinsky E, Rauen H M

出版信息

Hoppe Seylers Z Physiol Chem. 1970 Mar;351(3):377-83.

PMID:5420710
Abstract
摘要

相似文献

1
[Hypothetical metabolites of 2-bis(2-chloroethyl)amino-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide (cyclophosphamide)].
Hoppe Seylers Z Physiol Chem. 1970 Mar;351(3):377-83.
2
[Competitive inhibition of the metabolism of 2(bis-(2-chlorethyl)-amino)-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide by phenylbutazone and phenobarbital in the rat].
Arzneimittelforschung. 1970 Dec;20(12):1879-81.
3
Comparative metabolism of 2-[bis(2-chloroethyl)amino]tetrahydro-2-H-1,3,2-oxazaphosphorine-2-oxide (cyclophosphamide) and its enantiomers in humans.2-[双(2-氯乙基)氨基]四氢-2-H-1,3,2-恶唑磷-2-氧化物(环磷酰胺)及其对映体在人体内的比较代谢
Cancer Res. 1979 Jul;39(7 Pt 1):2762-7.
4
[Pharmacokinetics of cyclophosphamide and cyclophosphamide metabolites in the mouse and their influence on the therapeutic effect of "activated" cyclophosphamide (4-hydroxycyclophosphamide) (author's transl)].环磷酰胺及其代谢产物在小鼠体内的药代动力学及其对“活化”环磷酰胺(4-羟基环磷酰胺)治疗效果的影响(作者译)
Arzneimittelforschung. 1982;32(6):639-47.
5
Mass spectrometric characterization of activated N-(2-chloroethyl)amino oxazaphosphorine derivative.活化的N-(2-氯乙基)氨基口恶唑磷衍生物的质谱表征
Biomed Mass Spectrom. 1977 Aug;4(4):209-15. doi: 10.1002/bms.1200040404.
6
Metabolism of iphosphamide (2-(2-chloroethylamino)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide) and production of a toxic iphosphamide metabolite.
Cancer Res. 1973 May;33(5):1016-22.
7
[Isolation and characterisation of two main metabolites of ifosfamide from human urine (author's transl)].人尿中异环磷酰胺两种主要代谢物的分离与鉴定(作者译)
Arzneimittelforschung. 1976;26(7):1376-7.
8
Synthesis of deuterium-labeled analogs of cyclophosphamide and its metabolites.环磷酰胺及其代谢物的氘标记类似物的合成。
J Med Chem. 1975 Nov;18(11):1102-6. doi: 10.1021/jm00245a011.
9
[Origin and level of N,N-bis-(2-chloroethyl)-amine in serum after the injection of N,N-bis-(2-chloroethyl)-N',O-propylenephosphoric-acid-ester-diamide].
Arzneimittelforschung. 1966 Nov;16(11):1529-33.
10
[Selective effect of N,N-bis-(2-chloroethyl)-N1,O-propylenephosphoric acid ester-diamide and analogues on the CAM-tumor system].
Arzneimittelforschung. 1968 Jan;18(1):105-9.

引用本文的文献

1
Oxidation of cyclophosphamide by means of KMnO 4 .通过高锰酸钾对环磷酰胺进行氧化。
Experientia. 1972 May 15;28(5):536-7. doi: 10.1007/BF01931863.
2
[Metabolic pathways of cyclophosphamide].
Klin Wochenschr. 1972 May 1;50(9):449-53. doi: 10.1007/BF01487599.