Randolph S E
Parasitology. 1979 Aug;79(1):141-56. doi: 10.1017/s0031182000052033.
Attachment, engorgement and subsequent development of successive infestations of Ixodes trianguliceps larvae and nymphs on natural hosts, Apodemus sylvaticus, and unnatural hosts, laboratory mice, are compared. In laboratory mice, primary infestations above a threshold level of about 10 ticks elicit an immunological response which reduces, in a density-dependent manner, the rate of successful tick engorgement during subsequent infestations. In contrast, in A. sylvaticus successive infestations of larvae result in unchanged or slightly improved survival through to nymphs. The relevance of these results to the concept of host-parasite co-evolution and to tick population regulation is discussed.
比较了三角硬蜱幼虫和若虫在自然宿主林姬鼠以及非自然宿主实验室小鼠上的附着、饱血情况，以及后续连续侵染的发展情况。在实验室小鼠中，当首次侵染的蜱虫数量超过约10只的阈值水平时，会引发免疫反应，该反应会以密度依赖的方式降低后续侵染期间蜱虫成功饱血的速率。相比之下，在林姬鼠中，幼虫的连续侵染会使发育至若虫阶段的存活率保持不变或略有提高。讨论了这些结果与宿主-寄生虫协同进化概念以及蜱虫种群调控的相关性。
