Ambler J, Green A G, Pulvertaft C N
Gut. 1970 Mar;11(3):255-7. doi: 10.1136/gut.11.3.255.
Total serum alkaline phosphatase (SAP) activity has been measured in 463 men with partial gastrectomy (Polya type), and in a control group of 271 men with vagotomy with pyloroplasty or gastroenterostomy. An analysis of variance of the values in the range of 3.0 to 11.5 KA units/100 ml showed that the enzyme serum activity is influenced by three independent factors: age, ABO blood group, and the type of operation. Marginally raised levels (12.0-17.0 KA units/100 ml) were found to be affected by the same factors, and it was concluded that these levels do not, usually, indicate either bone or liver disease. In 18 men the total serum alkaline phosphatase was over 17.0 KA units: 16 had Paget's disease of bone, and two had liver disease.
对463例接受部分胃切除术(Polya术式)的男性患者以及271例接受迷走神经切断术加幽门成形术或胃肠吻合术的男性对照组患者,测定了血清总碱性磷酸酶(SAP)活性。对3.0至11.5 KA单位/100 ml范围内的值进行方差分析表明,酶的血清活性受三个独立因素影响:年龄、ABO血型和手术类型。发现轻度升高水平(12.0 - 17.0 KA单位/100 ml)受相同因素影响,得出的结论是,这些水平通常并不表明存在骨骼或肝脏疾病。在18例男性中,血清总碱性磷酸酶超过17.0 KA单位:16例患有骨Paget病,2例患有肝脏疾病。