Gaziano D, Seaton A, Ogilvie C
Br Med J. 1970 May 9;2(5705):330-3. doi: 10.1136/bmj.2.5705.330.
Regional lung function was measured, using radioactive xenon-133, in a group of normal subjects and in three carefully defined groups of patients with obstructive lung disease. When compared with the normal subjects, patients in the emphysematous group showed a relative reduction of ventilation and perfusion to the upper zones, while patients having chronic bronchitis without cardiac or respiratory failure showed a predominantly lower zone defect. In the group of patients with chronic bronchitis with cardiac and respiratory failure no consistent pattern was found.
使用放射性氙 - 133对一组正常受试者以及三组经过严格定义的阻塞性肺疾病患者进行了区域肺功能测量。与正常受试者相比,肺气肿组患者上肺区的通气和灌注相对减少,而无心脏或呼吸衰竭的慢性支气管炎患者主要表现为下肺区缺陷。在伴有心脏和呼吸衰竭的慢性支气管炎患者组中,未发现一致的模式。