Richter W, Fleischer J, Irmscher J
Folia Haematol Int Mag Klin Morphol Blutforsch. 1975;102(5):524-9.
4 cases of chronic monocytic leukemia were observed during several years. In 2 patients there was a final appearance of blastic crisis. During the course of the disease the activity of the naphthylacetate-esterase in the monocytes increased, but the PAS-reaction was lowered. By the help of two cases for comparison - one patient suffering from a chronic myeloid leukemia and intermediate monocytic phase, the other one from a panmyelopathia and monocytic reaction - the morphological resemblance of these phenomena is demonstrated, which cytochemically cannot be separated.
数年间观察了4例慢性单核细胞白血病。2例患者最终出现原始细胞危象。在疾病过程中,单核细胞中萘乙酸酯酶的活性增加,但过碘酸雪夫反应降低。借助2例对照病例——1例患有慢性髓细胞白血病并处于中间单核细胞期,另1例患有全髓病并伴有单核细胞反应——证明了这些现象在形态学上的相似性,在细胞化学上无法区分。