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[低温对冬眠后地松鼠氨-谷氨酰胺-谷氨酸系统的影响]

[Effect of hypothermia on the ammonia-glutamine-glutamic acid system in ground squirrels after hibernation].

作者信息

Emirbekov E Z, Ismanlov I A

出版信息

Ukr Biokhim Zh (1978). 1979 Nov-Dec;51(6):684-6.

PMID:543034
Abstract

The effect of forced cooling was studied as applied to the contents of ammonia, glutamine, glutaminic, asparaginic and alpha-amino butyric acids in the brain of sousliks woken-from hibernation. The cooling of the woken sousliks to the body temperature of 30, 20 and 25 degrees C decreased to some extent the ammonia content in the brain. A deeper hypothermia (10 degrees C) causes its 60,4% decrease as compared to the ammonia amount in woken animals. The cooling of the animals to 30, 25, 20 and 10 degrees C considerably decreases the contents of glutamine, glutaminic acid and GABA in the brain tissue.

摘要

研究了强制冷却对从冬眠中苏醒的黄鼠大脑中氨、谷氨酰胺、谷氨酸、天冬酰胺和α-氨基丁酸含量的影响。将苏醒的黄鼠冷却至30、20和25摄氏度的体温,在一定程度上降低了大脑中的氨含量。与苏醒动物的氨含量相比,更深的低温(10摄氏度)使其降低了60.4%。将动物冷却至30、25、20和10摄氏度,会显著降低脑组织中谷氨酰胺、谷氨酸和γ-氨基丁酸的含量。

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