Gola A
Folia Haematol Int Mag Klin Morphol Blutforsch. 1975;102(5):550-8.
In 33 patients with chronic lymphatic leukaemia (CLL) the lipids were examined quantitatively and qualitatively in the serum and in the lymphocytes. Besides the 5 main categories of lipids, lysolecithin, sphingomyelin, lecithin and cephalin as well as cholesterol ester subfractions were determined according to their degree of saturation of their fatty acids. Patients suffering from CLL were found to have a moderately raise of serum triglycerides and an increase of cholesterol esters with simple unsaturated fatty acids. Simultaneously the fraction of ester with poly-unsaturated fatty acids is lowered. Leukaemic lymphocytes reveal in general a lowered total lipid content. It mainly consists of phosphatides and free cholesterol. Moreover, the leukaemic lymphocytes contrary to normal ones reveal a lowered content of cholesterol esters, diglycerides and triglycerides.
对33例慢性淋巴细胞白血病（CLL）患者的血清和淋巴细胞中的脂质进行了定量和定性检测。除了5大类脂质外，还根据溶血卵磷脂、鞘磷脂、卵磷脂和脑磷脂以及胆固醇酯亚组分中脂肪酸的饱和程度进行了测定。发现CLL患者血清甘油三酯适度升高，含单不饱和脂肪酸的胆固醇酯增加。同时，含多不饱和脂肪酸的酯的比例降低。白血病淋巴细胞总体上显示总脂质含量降低。它主要由磷脂和游离胆固醇组成。此外，与正常淋巴细胞相反，白血病淋巴细胞的胆固醇酯、甘油二酯和甘油三酯含量降低。
