Kann V, Bürgermeister W, Wawschinek O
Wien Med Wochenschr. 1979 Dec 15;129(23):667-9.
In a case of severe poisoning with the organophosphorous insecticide methidathione standardized forced diuresis and peritoneal dialysis were performed for the first time in addition to the usual therapeutical procedures (e.g. repeated gastric lavage, induced diarrhea, atropine and intensive care). The course of the illness as well as the duration of the acute phase were significantly shorter than in comparable cases. No hazardous situation occurred after the first hours of treatment. The presence of the organophosphorous cholinesterase inhibitor or of its metabolites in the urine and the dialysate was proved by thin-layer chromatography.
在一例重度甲拌磷有机磷杀虫剂中毒病例中,除常规治疗措施(如反复洗胃、诱导腹泻、使用阿托品及重症监护)外,首次进行了标准化强制利尿和腹膜透析。与可比病例相比,病程及急性期持续时间显著缩短。治疗最初数小时后未出现危险情况。通过薄层色谱法证实尿液和透析液中存在有机磷胆碱酯酶抑制剂或其代谢产物。