Takeuchi K
Int J Clin Pharmacol Biopharm. 1975 Dec;12(4):419-26.
The author has carried out the administration of bleomycin, chiefly by the intravenous route, in the postoperative adjuvant treatment of 150 cases of brain tumor since January 1969. The overall response rate of gliomas to bleomycin was more than 50 per cent. No distinct, given tendency toward possible differences in bleomycin effectiveness due to the type and location of tumors was revealed, but it appears that there were fewer effective cases among highly malignant gliomas and metastitic brain tumors. The survival data also showed encouraging results.
自1969年1月起，作者主要通过静脉途径给予博来霉素，对150例脑肿瘤患者进行术后辅助治疗。胶质瘤对博来霉素的总体缓解率超过50%。未发现因肿瘤类型和位置不同而导致博来霉素疗效有明显的特定差异倾向，但高度恶性胶质瘤和脑转移瘤中的有效病例似乎较少。生存数据也显示出令人鼓舞的结果。
