成人乳糜泻患者肠道黏膜的肽水解酶活性
Peptide hydrolase activity of human intestinal mucosa in adult coeliac disease.
作者信息
Douglas A P, Peters T J
出版信息
Gut. 1970 Jan;11(1):15-7. doi: 10.1136/gut.11.1.15.
Abstract
The levels of two peptide hydrolases were studied in intestinal mucosa from normal subjects, patients with untreated coeliac disease, and treated patients. The mucosa from the untreated patients had significantly reduced activity against glycyl-glycine and leucylleucine. No such difference was found for the treated patients and it was concluded that the reduction in peptidase activity was secondary to the mucosal damage.
摘要
研究了正常受试者、未经治疗的乳糜泻患者和已治疗患者的肠黏膜中两种肽水解酶的水平。未经治疗患者的肠黏膜对甘氨酰甘氨酸和亮氨酰亮氨酸的活性显著降低。已治疗患者未发现此类差异，得出的结论是肽酶活性降低是黏膜损伤的继发结果。
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