• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

1,3-Bis(p-chlorobenzylideneamino)guanidine hydrochloride (robenzidene): new poultry anticoccidial agent.

作者信息

Kantor S, Kennett R L, Waletzky E, Tomcufcik A S

出版信息

Science. 1970 Apr 17;168(3929):373-4. doi: 10.1126/science.168.3929.373.

DOI:10.1126/science.168.3929.373
PMID:5435895
Abstract

At 66 parts per million in the feed, robenzidene is highly effective in preventing chicken coccidiosis caused by any one of eight Eimeria species. Three times this dose is safe for broiler chickens. In dogs and rats, the toxicity was relatively low over a period of 90 days. In laboratory trials, the drug completely prevents oocyst production by seven species and greatly reduces oocyst production by Eimeria maxima.

摘要

相似文献

1
1,3-Bis(p-chlorobenzylideneamino)guanidine hydrochloride (robenzidene): new poultry anticoccidial agent.
Science. 1970 Apr 17;168(3929):373-4. doi: 10.1126/science.168.3929.373.
2
Efficacy evaluations of robenzidene for control of coccidiosis in chickens.罗布齐登对鸡球虫病防治效果的评估。
Avian Dis. 1970 Nov;14(4):788-96.
3
Studies on the mode of action of the coccidiostat robenidene.抗球虫药罗贝尼丁作用方式的研究。
Z Parasitenkd. 1971;37(2):85-93. doi: 10.1007/BF00259551.
4
Coccidiosis: evaluation of coccidiostats by mortality, weight gains, and fecal scores.球虫病：通过死亡率、体重增加和粪便评分评估抗球虫药
Exp Parasitol. 1970 Aug;28(1):25-9. doi: 10.1016/0014-4894(70)90062-7.
5
Efficacy studies with robenidine, a new type of anticoccidial, in the diet.
Poult Sci. 1974 May;53(3):978-86. doi: 10.3382/ps.0530978.
6
The drug sensitivity of recently isolated strains of Eimeria meleagrimitis and a laboratory strain of Eimeria adenoeides in turkeys to robenidene.近期分离的火鸡孔雀艾美耳球虫菌株和火鸡腺状艾美耳球虫实验室菌株对罗苯哒唑的药物敏感性。
Res Vet Sci. 1972 May;13(3):279-81.
7
Eimeria Oocyst Concentrations and Species Composition in Litter from Commercial Broiler Farms During Anticoccidial Drug or Live Eimeria Oocyst Vaccine Control Programs.在抗球虫药或活艾美耳球虫卵囊疫苗控制方案期间，商业肉鸡场垫料中艾美耳球虫卵囊浓度及种类组成
Avian Dis. 2017 Jun;61(2):214-220. doi: 10.1637/11578-010317-Reg.1.
8
Coccidiosis: evaluation of anticoccidial drugs in floor-pen trials.
Exp Parasitol. 1970 Aug;28(1):64-71. doi: 10.1016/0014-4894(70)90067-6.
9
Comparison of the anticoccidial effect of granulated extract of Artemisia sieberi with monensin in experimental coccidiosis in broiler chickens.西伯蒿颗粒提取物与莫能菌素对肉鸡实验性球虫病抗球虫效果的比较
Exp Parasitol. 2014 Jun;141:129-33. doi: 10.1016/j.exppara.2014.03.022. Epub 2014 Apr 2.
10
Anticoccidial drugs: lesion scoring techniques in battery and floor-pen experiments with chickens.抗球虫药：鸡笼养和地面平养实验中的病变评分技术
Exp Parasitol. 1970 Aug;28(1):30-6. doi: 10.1016/0014-4894(70)90063-9.

引用本文的文献

1
Mass Balance Studies of Robenidine Hydrochloride in the Body of Channel Catfish ().斑点叉尾鮰体内盐酸氯苯胍的质量平衡研究（）
Animals (Basel). 2023 Dec 4;13(23):3745. doi: 10.3390/ani13233745.
2
Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces infection and reduces infection in combination with sub-inhibitory colistin concentrations in a bioluminescent mouse model.口服 2-氨基嘧啶类罗贝林类似物（NCL195）可显著降低感染，并与亚抑菌浓度的黏菌素联合使用时可降低感染，在生物发光小鼠模型中。
Antimicrob Agents Chemother. 2023 Oct 18;67(10):e0042423. doi: 10.1128/aac.00424-23. Epub 2023 Sep 11.
3
Mononuclear/Binuclear [VO]/[VO] Complexes Derived from 1,3-Diaminoguanidine and Their Catalytic Application for the Oxidation of Benzoin via Oxygen Atom Transfer.
源自1,3-二氨基胍的单核/双核[VO]/[VO]配合物及其通过氧原子转移催化安息香氧化的应用。
ACS Omega. 2022 Dec 16;8(1):1301-1318. doi: 10.1021/acsomega.2c06732. eCollection 2023 Jan 10.
4
In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens.洛贝胍类似物NCL259和NCL265对革兰氏阴性病原体的体外活性
Antibiotics (Basel). 2022 Sep 23;11(10):1301. doi: 10.3390/antibiotics11101301.
5
Robenidine Analogues Are Potent Antimalarials in Drug-Resistant .罗贝林类似物是耐药性. 的强效抗疟药。
ACS Infect Dis. 2021 Jul 9;7(7):1956-1968. doi: 10.1021/acsinfecdis.1c00001. Epub 2021 Mar 16.
6
FDA Approved Drug Library Screening Identifies Robenidine as a Repositionable Antifungal.美国食品药品监督管理局批准的药物库筛选确定罗苯尼丁为一种可重新定位的抗真菌药物。
Front Microbiol. 2020 Jun 3;11:996. doi: 10.3389/fmicb.2020.00996. eCollection 2020.
7
In vitro Antibacterial Activity of Isopropoxy Benzene Guanidine Against Multidrug-Resistant .异丙氧基苯胍对多重耐药菌的体外抗菌活性
Infect Drug Resist. 2019 Dec 23;12:3943-3953. doi: 10.2147/IDR.S234509. eCollection 2019.
8
The antibiotic robenidine exhibits guanabenz-like cytoprotective properties by a mechanism independent of protein phosphatase PP1:PPP1R15A.抗生素罗贝林通过一种独立于蛋白磷酸酶 PP1 的机制表现出胍丁胺样的细胞保护特性：PPP1R15A。
J Biol Chem. 2019 Sep 6;294(36):13478-13486. doi: 10.1074/jbc.RA119.008857. Epub 2019 Jul 23.
9
Antimicrobial Activity of Robenidine, Ethylenediaminetetraacetic Acid and Polymyxin B Nonapeptide Against Important Human and Veterinary Pathogens.氯苯胍、乙二胺四乙酸和多粘菌素B九肽对重要的人类和兽医病原体的抗菌活性
Front Microbiol. 2019 Apr 25;10:837. doi: 10.3389/fmicb.2019.00837. eCollection 2019.
10
Aminoguanidines: New leads for treatment of Giardia duodenalis infection.氨胍类药物：治疗十二指肠贾第鞭毛虫感染的新线索。
Int J Parasitol Drugs Drug Resist. 2019 Aug;10:38-44. doi: 10.1016/j.ijpddr.2019.04.003. Epub 2019 Apr 8.