Sutton R A
Br Med J. 1970 Feb 28;1(5695):529-33. doi: 10.1136/bmj.1.5695.529.
The plasma magnesium concentration has been determined in 73 patients with primary hyperparathyroidism. In most patients it lay within the normal range (1.7-2.3 mg./100 ml.), but in five it was less than 1.6 mg./100 ml. These patients had relatively high urinary magnesium outputs, and one of them, studied in greater detail, failed to retain parenterally administered magnesium. Hence hypomagnesaemia in hyperparathyroidism may be associated with a defect in renal magnesium conservation, which may be reversible.
对73例原发性甲状旁腺功能亢进患者测定了血浆镁浓度。大多数患者的血浆镁浓度在正常范围内(1.7 - 2.3毫克/100毫升),但有5例低于1.6毫克/100毫升。这些患者的尿镁排出量相对较高,其中1例进行了更详细的研究,未能保留经胃肠外给予的镁。因此,甲状旁腺功能亢进症中的低镁血症可能与肾脏对镁的保留缺陷有关,这种缺陷可能是可逆的。