Porter J F, Young J A, Mitchell R G
Arch Dis Child. 1970 Feb;45(239):54-8. doi: 10.1136/adc.45.239.54.
Blood and plasma histamine levels, together with circulating basophil and eosinophil counts, were estimated in a group of asthmatic children. Short-term studies were carried out on 7 patients, each of whom was given a single dose of corticosteroid, and the effects of the hormone were monitored for periods of up to two hours. Usually a fall occurred in the whole blood histamine level, basophil count, and eosinophil count, but no change occurred in the plasma histamine level, which remained very low throughout. In 3 cases, follow-up studies showed that in 2 cases out of 3, whole blood histamine levels were lower during treatment with corticosteroids, than when steroids were not being given.
对一组哮喘儿童测定了血液和血浆中的组胺水平，以及循环中的嗜碱性粒细胞和嗜酸性粒细胞计数。对7名患者进行了短期研究，每名患者均给予单剂量皮质类固醇，并监测该激素长达两小时的效果。通常全血组胺水平、嗜碱性粒细胞计数和嗜酸性粒细胞计数会下降，但血浆组胺水平没有变化，且始终保持在很低的水平。在3例随访研究中，结果显示3例中有2例，皮质类固醇治疗期间的全血组胺水平低于未给予类固醇时。
