口服普萘洛尔治疗高血压患者的血流动力学研究。
Haemodynamic studies in hypertensive patients treated by oral proranolol.
作者信息
Prichard B N, Shinebourne E, Fleming J, Hamer J
出版信息
Br Heart J. 1970 Mar;32(2):236-40. doi: 10.1136/hrt.32.2.236.
Abstract
Haemodynamic studies have been performed in 9 patients whose blood pressures had been satisfactorily controlled with oral propranolol for 7 to 29 months. A postural drop of blood pressure or a fall of blood pressure on exercise did not occur. Pulse rate and cardiac output were below normal at rest and on exercise; peripheral resistance was high. The results are similar to those obtained in a comparable group of hypertensives after acute administration of propranolol. These findings are discussed in relation to the mode of action of propranolol in hypertension.
摘要
对9例患者进行了血流动力学研究，这些患者口服普萘洛尔后血压得到满意控制达7至29个月。未出现体位性血压下降或运动时血压下降。静息和运动时脉搏率和心输出量均低于正常；外周阻力较高。这些结果与一组类似高血压患者急性给予普萘洛尔后获得的结果相似。结合普萘洛尔在高血压中的作用方式对这些发现进行了讨论。
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