对卤化麻醉剂反应异常的猪的血清肌酸磷酸激酶水平。
Serum creatine phosphokinase levels in pigs reacting abnormally to halogenated anaesthetics.
作者信息
Woolf N, Hall L, Thorne C, Down M, Walker R
出版信息
Br Med J. 1970 Aug 15;3(5719):386-7. doi: 10.1136/bmj.3.5719.386.
Abstract
Serum levels of creatine phosphokinase (CPK) were estimated in pigs. Among those known to react abnormally either to halothane alone or to halothane and suxamethonium most had very high levels of CPK. Twenty-four hours after five minutes' anaesthesia with halothane and oxygen a sustained, pronounced rise in the serum CPK occurred in some pigs-principally but not exclusively in the abnormal reactors. Estimation of the serum level of CPK may be a useful screening test for an abnormal hyperpyrexial response to halothane.
摘要
对猪的血清肌酸磷酸激酶（CPK）水平进行了评估。在那些已知单独对氟烷或对氟烷和琥珀胆碱反应异常的猪中，大多数CPK水平非常高。在用氟烷和氧气麻醉五分钟后24小时，一些猪的血清CPK出现持续、明显升高，主要但不限于异常反应者。测定血清CPK水平可能是一种有用的筛选试验，用于检测对氟烷的异常高热反应。
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本文引用的文献
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Br Med J. 1965 Mar 20;1(5437):750-3. doi: 10.1136/bmj.1.5437.750.
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Unusual reaction to suxamethonium chloride.对氯化琥珀胆碱的异常反应。
Br Med J. 1966 Nov 26;2(5525):1305. doi: 10.1136/bmj.2.5525.1305.
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Malignant hyperpyrexia during anaesthesia: possible association with subclinical myopathy.麻醉期间的恶性高热：可能与亚临床肌病有关。
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Myopathy and malignant hyperpyrexia.
Lancet. 1970 May 30;1(7657):1138-40. doi: 10.1016/s0140-6736(70)91215-8.
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