Chihara E, Nishi R, Asayama K, Tsukahara I
Ophthalmologica. 1979;179(5):258-64. doi: 10.1159/000308904.
3 early Mooren's ulcers were successfully treated by only one-time conjunctival excision adjacent to the ulcer, while in 2 other chronic vascularized Mooren's ulcers, repeated conjunctival excision was required for a final remission. The clinical outcome of these 5 eyes was better than that of 7 other eyes treated by conjunctival flap procedure, lamellar keratoplasty, topical eye drops or systemic medications. Four fragments of excised conjunctival tissue were examined histopathologically; the substantia propria was found to be infiltrated with plasma cells.
3例早期蚕蚀性角膜溃疡仅通过一次溃疡旁结膜切除术就成功治愈,而另外2例慢性血管化蚕蚀性角膜溃疡则需要反复进行结膜切除术才能最终缓解。这5只眼的临床结果优于另外7只接受结膜瓣手术、板层角膜移植术、局部滴眼液或全身药物治疗的眼睛。对切除的结膜组织的4个片段进行了组织病理学检查;发现固有层有浆细胞浸润。