Klastersky J
Nouv Rev Fr Hematol (1978). 1979;Suppl:XIX-XXI.
Rational antimicrobial therapy in neutropenic patients includes early empiric therapy with combinations of antibiotics active in vitro against the causal pathogen. The duration of therapy is to be adapted to the clinical response. In patients who do not respond to antimicrobial therapy, transfusion of granulocytes and empiric use of antifungal drugs should be considered.
中性粒细胞减少患者的合理抗菌治疗包括早期经验性治疗，使用体外对致病病原体有活性的抗生素联合用药。治疗持续时间应根据临床反应进行调整。对于对抗菌治疗无反应的患者，应考虑输注粒细胞并经验性使用抗真菌药物。
