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猪沙门氏菌病。II. 通过静脉注射猪霍乱沙门氏菌破碎细胞引发全身性施瓦茨曼反应

Porcine salmonellosis. II. Production of the generalized Shwartzman reaction by intravenous injections of disintegrated cells of salmonella cholerae-suis.

作者信息

Nordstoga K, Fjölstad M

出版信息

Acta Vet Scand. 1970;11(3):370-9. doi: 10.1186/BF03547964.

Abstract

Three pigs were given intravenous injections of disintegrated cells of Salmonella cholerae-suis. One of these pigs developed macroscopic bilateral renal cortical necrosis. Histologic examination revealed, besides total cortical parenchymal necrosis, also severe vascular injury, characterized with fibrinoid necrosis of the vessel walls and fibrin thrombi within their lumina. These findings were interpreted as a result of a generalized Shwartzman reaction, provoked by the action of bacterial endotoxin.

摘要

给三只猪静脉注射猪霍乱沙门氏菌的破碎细胞。其中一只猪出现了肉眼可见的双侧肾皮质坏死。组织学检查显示,除了整个皮质实质坏死外,还存在严重的血管损伤,其特征为血管壁的纤维蛋白样坏死以及管腔内的纤维蛋白血栓。这些发现被解释为由细菌内毒素作用引发的全身性施瓦茨曼反应的结果。

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引用本文的文献

本文引用的文献

1
PRODUCTION OF THE GENERALISED SHWARTZMAN REACTION WITH SALMONELLA CHOLERAE-SUIS.
J Comp Pathol. 1964 Oct;74:482-6. doi: 10.1016/s0368-1742(64)80054-0.
3
Mechanisms of the hemodynamic effects of endotoxin.内毒素血流动力学效应的机制。
Physiol Rev. 1960 Apr;40:245-79. doi: 10.1152/physrev.1960.40.2.245.
4
Porcine salmonellosis. A study of the field disease.
J Comp Pathol. 1966 Oct;76(4):363-71. doi: 10.1016/0021-9975(66)90056-9.

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