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Isolation and identification of 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methylthiazole-5-acetic acid (thiamine acetic acid) and 2-methyl-4-amino-5-formylaminomethylpyrimidine as metabolites of thiamine in the rat.

作者信息

Amos W H, Neal R A

出版信息

J Biol Chem. 1970 Nov 10;245(21):5643-8.

PMID:5472363
Abstract
摘要

相似文献

1
Isolation and identification of 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methylthiazole-5-acetic acid (thiamine acetic acid) and 2-methyl-4-amino-5-formylaminomethylpyrimidine as metabolites of thiamine in the rat.大鼠体内硫胺素代谢产物3-(2'-甲基-4'-氨基-5'-嘧啶基甲基)-4-甲基噻唑-5-乙酸（硫胺素乙酸）和2-甲基-4-氨基-5-甲酰氨基甲基嘧啶的分离与鉴定
J Biol Chem. 1970 Nov 10;245(21):5643-8.
2
Bacterial metabolism of thiamine. II. The isolation and characterization of 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methylthiazole-5-acetic acid (thiamine acetic acid) as an intermediate in the oxidation of thiamine.硫胺素的细菌代谢。II. 3-(2'-甲基-4'-氨基-5'-嘧啶基甲基)-4-甲基噻唑-5-乙酸（硫胺素乙酸）作为硫胺素氧化中间体的分离与表征
J Biol Chem. 1969 Oct 10;244(19):5201-5.
3
4-Methylthiazole-5-acetic acid--a urinary metabolite of thiamine.
J Nutr. 1968 Dec;96(4):445-9. doi: 10.1093/jn/96.4.445.
4
The occurrence of 4-methylthiazole-5-acetic acid as a thiamine metabolite in rabbit, dog, man and rat.4-甲基噻唑-5-乙酸作为硫胺素代谢物在兔、狗、人和大鼠体内的出现情况。
J Biochem. 1969 Jun;65(6):953-60. doi: 10.1093/oxfordjournals.jbchem.a129100.
5
Identification of 4-methylthiazole-5-acetic acid in the urine of rats after oral administration of thiamine.口服硫胺素后大鼠尿液中4-甲基噻唑-5-乙酸的鉴定。
J Biochem. 1968 Jun;63(6):792-4. doi: 10.1093/oxfordjournals.jbchem.a128845.
6
Metabolism of thiamine and thiamine tetrahydro-furfuryl disulfide to 4-methylthiazole-5-acetic acid in conventional and germfree rats under various dosing conditions.在不同给药条件下，常规大鼠和无菌大鼠体内硫胺素及四氢糠基二硫化物硫胺素代谢生成4-甲基噻唑-5-乙酸的情况。
J Nutr. 1968 Dec;96(4):433-44. doi: 10.1093/jn/96.4.433.
7
Catabolites of thiamine from the rat.来自大鼠的硫胺素分解代谢产物。
Nutr Rev. 1971 May;29(5):119-21. doi: 10.1111/j.1753-4887.1971.tb07265.x.
8
Thiamin metabolism in man.人体中的硫胺素代谢
Am J Clin Nutr. 1970 Jun;23(6):764-78. doi: 10.1093/ajcn/23.6.764.
9
Isolation and identification of the pyrimidine moiety of thiamin in rat urine using gas chromatography-mass spectrometry.
J Nutr. 1970 Sep;100(9):1053-6. doi: 10.1093/jn/100.9.1053.
10
Bacterial metabolism of thiamine. 3. Metabolism of thiamine to 3-(2'-methyl-4'-amino-5'-pyrimidylmethyl)-4-methyl-thiazole-5-acetic acid (thiamine acetic acid) by a flavoprotein isolated from a soil microorganism.硫胺素的细菌代谢。3. 从土壤微生物中分离出的一种黄素蛋白将硫胺素代谢为3-(2'-甲基-4'-氨基-5'-嘧啶基甲基)-4-甲基噻唑-5-乙酸（硫胺素乙酸）。
J Biol Chem. 1970 May 25;245(10):2599-604.

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Comparative Genomic and Genetic Evidence on a Role for the OarX Protein in Thiamin Salvage.关于OarX蛋白在硫胺素挽救中作用的比较基因组学和遗传学证据。
ACS Omega. 2024 Jun 21;9(26):28888-28894. doi: 10.1021/acsomega.4c03514. eCollection 2024 Jul 2.
2
A novel PET tracer F-deoxy-thiamine: synthesis, metabolic kinetics, and evaluation on cerebral thiamine metabolism status.一种新型正电子发射断层显像（PET）示踪剂F-脱氧硫胺素：合成、代谢动力学及脑硫胺素代谢状态评估
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3
Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine.
缺乏活性位点半胱氨酸的植物TenA蛋白对硫胺嘧啶部分的挽救作用。
Biochem J. 2014 Oct 1;463(1):145-55. doi: 10.1042/BJ20140522.