阳离子环寡聚（乙烯腺嘌呤）的合成。

Synthesis of cationic cyclo-oligo(ethyleneadenine).

作者信息

Shimidzu T, Kanou T, Murakami A, Yamana K

出版信息

Nucleic Acids Symp Ser. 1979(6):s57-60.

Abstract

A novel cationic and cyclic oligo (ethyleneadenine) whose main chain has adenine ring was synthesized by the thermal polymerization of 9-(2-bromoethyl) adenine, in the solid phase. The chain extends through N-9 - N-1 and N-9 - N-7 of the adenine rings. Its molecular weight was determined to be 3960 by the sedimentation method. The micro-structure was confirmed mainly with NMR measurements. The cationic and cyclic oligo(ethyleneadenine) interacts with nucleotides and polynucleotides in neutral aqueous solution.

摘要

通过9-(2-溴乙基)腺嘌呤在固相中的热聚合反应，合成了一种新型的阳离子环状寡聚(乙烯腺嘌呤)，其主链含有腺嘌呤环。该链通过腺嘌呤环的N-9 - N-1和N-9 - N-7延伸。用沉降法测定其分子量为3960。主要通过核磁共振测量确定其微观结构。在中性水溶液中，阳离子环状寡聚(乙烯腺嘌呤)与核苷酸和多核苷酸相互作用。

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