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睾丸女性化综合征:3例埃塞俄比亚患者的报告及简要综述

Testicular feminization syndrome: a report of three Ethiopian patients and a brief review.

作者信息

Tsega E, Damtew B

出版信息

Postgrad Med J. 1979 Nov;55(649):844-8. doi: 10.1136/pgmj.55.649.844.

DOI:10.1136/pgmj.55.649.844
PMID:547282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2425783/
Abstract

The clinical features of 3 Ethiopian patients presenting with the complete syndrome of testicular feminization are described. All 3 were seen because of primary amenorrhoea. At laparotomy, one patient had testes located intra-abdominally, a second lodged in the inguinal canals and a third as masses in the labia majora. Also, one of these patients had bilateral inguinal herniae, a usual feature of this syndrome. Since the incidence of malignancy is high among individuals with undescended testes, they were removed in 2 patients. In the third patient, however, the testes were not removed because of delay in development of secondary sex characteristics. The literature on testicular feminization is also briefly reviewed.

摘要

本文描述了3例呈现完全性睾丸女性化综合征的埃塞俄比亚患者的临床特征。所有3例患者均因原发性闭经前来就诊。剖腹探查时,1例患者的睾丸位于腹腔内,第2例位于腹股沟管,第3例为大阴唇肿物。此外,其中1例患者患有双侧腹股沟疝,这是该综合征的常见特征。由于隐睾患者发生恶性肿瘤的几率较高,2例患者的睾丸被切除。然而,第3例患者的睾丸未被切除,原因是第二性征发育延迟。本文还简要回顾了关于睾丸女性化的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6251/2425783/5815ae136a49/postmedj00251-0075-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6251/2425783/94245e57bbb1/postmedj00251-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6251/2425783/e2349c313b61/postmedj00251-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6251/2425783/5815ae136a49/postmedj00251-0075-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6251/2425783/94245e57bbb1/postmedj00251-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6251/2425783/e2349c313b61/postmedj00251-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6251/2425783/5815ae136a49/postmedj00251-0075-b.jpg

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1
Testicular feminization syndrome: a report of three Ethiopian patients and a brief review.睾丸女性化综合征:3例埃塞俄比亚患者的报告及简要综述
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本文引用的文献

1
Gynecological operations in 94 patients withintersexuality. Implications concerning the endocrine theory of sexual differentiation.
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2
FURTHER OBSERVATIONS ON THE SYNDROME, "TESTICULAR FEMINIZATION".关于“睾丸女性化”综合征的进一步观察
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3
The syndrome of testicular feminization in male pseudohermaphrodites.男性假两性畸形中的睾丸女性化综合征。
Am J Obstet Gynecol. 1953 Jun;65(6):1192-1211. doi: 10.1016/0002-9378(53)90359-7.
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Further evidence of a target organ defect in the syndrome of testicular feminization.睾丸女性化综合征中靶器官缺陷的进一步证据。
J Clin Endocrinol Metab. 1966 May;26(5):493-503. doi: 10.1210/jcem-26-5-493.
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Testicular feminization with and without clitoral enlargement.伴有或不伴有阴蒂增大的睾丸女性化。
Am J Obstet Gynecol. 1966 Mar 15;94(6):813-9.
6
Case records of the Massachusetts General Hospital. Weekly clinocopathological exercises. Case 8-1977.马萨诸塞州总医院病例记录。每周临床病理讨论。病例8 - 1977年
N Engl J Med. 1977 Feb 24;296(8):439-44. doi: 10.1056/NEJM197702242960808.
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Mechanism of action of the sex steroid hormones (first of three parts).性甾体激素的作用机制(三部分中的第一部分)
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