Morman M R, White D C
J Bacteriol. 1970 Oct;104(1):247-53. doi: 10.1128/jb.104.1.247-253.1970.
During membrane-bound penicillinase production, Bacillus licheniformis forms vesicles and tubules that do not appear in the absence of penicillinase production. The major lipids of B. licheniformis were shown to be phospholipids. The proportions, metabolism, and the total phospholipid per cell were shown to be essentially the same in the uninduced control, induced and constitutive penicillinase forming cells during both the exponential and stationary growth phases. Membrane phospholipids were not secreted into the medium during penicillinase formation. In the shift from the exponential to the stationary growth phase, there was an accumulation of phosphatidyl glycerol and a marked decrease in cardiolipin. These two lipids had the most active turnover of their phospholipid phosphate of all the lipids studied.
在产生膜结合青霉素酶的过程中,地衣芽孢杆菌会形成囊泡和小管,而在不产生青霉素酶时则不会出现。已证明地衣芽孢杆菌的主要脂质是磷脂。在指数生长期和稳定期,未诱导的对照细胞、诱导型和组成型青霉素酶形成细胞中的磷脂比例、代谢以及每个细胞的总磷脂量基本相同。在青霉素酶形成过程中,膜磷脂不会分泌到培养基中。从指数生长期转变到稳定生长期时,磷脂酰甘油会积累,而心磷脂则会显著减少。在所研究的所有脂质中,这两种脂质的磷脂磷酸周转最为活跃。