Fritsch P, Czarnecki N, Schuler G
Wien Klin Wochenschr. 1979 Dec 21;91(24):835-42.
This paper presents four unusual variants of blue naevus: a giant-sized blue naevus, a blue naevus assuming the clinical and histological appearance of a histiocytoma, a plaque-type blue naevus, and a pedunculated cellular blue naevus. Two of these lesions were studied at the ultrastructural level: in one case the dermal melanocytes contained malanosomes of all stages, thus documenting active melanin synthesis. In the other lesion, melanocytes of identical appearance were found in the superficial portions, whereas inactive melanocytes, densely packed with mature melanosomes, predominated in the deeper portions. It is concluded that blue naevi may vary considerably, both clinically and in histological appearance, as well as in regard to melanin synthesis activity.
巨大型蓝痣、具有组织细胞瘤临床和组织学表现的蓝痣、斑块型蓝痣以及带蒂细胞蓝痣。对其中两个病变进行了超微结构研究：在一个病例中，真皮黑素细胞含有各个阶段的黑素体，从而证明有活跃的黑色素合成。在另一个病变中，在浅表部分发现了外观相同的黑素细胞，而在较深部分则以充满成熟黑素体的不活跃黑素细胞为主。结论是，蓝痣在临床、组织学表现以及黑色素合成活性方面可能有很大差异。
