Heinrich J
Zentralbl Gynakol. 1979;101(24):1581-7.
Reported in this paper is the case of a patient, 19 years of age, with twin pregnancy who developed acute pregnancy-caused fatty degeneration of the liver with typical clinical symptoms in the 34th week of pregnancy, following nine weeks of hospitalisation for tocolysis treatment. The presence of a severe hepatorenal syndrome due to late gestosis, pregnancy cholestase or medicamentous intoxication is discussed for differential diagnosis. Suggestions are made as to high-dosage Partusisten long-time tocolysis which, possibly, might have been an additional hepatotoxic stress factor in concomitance with late gestosis.
本文报道了一例19岁双胎妊娠患者的病例,该患者在妊娠34周时出现典型临床症状的急性妊娠性脂肪肝,此前因保胎治疗住院9周。讨论了因晚期妊娠中毒症、妊娠胆汁淤积或药物中毒导致严重肝肾综合征的鉴别诊断。对于高剂量利托君长时间保胎治疗提出了建议,这可能是与晚期妊娠中毒症同时存在的另一个肝毒性应激因素。