Papanayiotou P, Papanayiotou K, Dontas A S, Marketos S G
Postgrad Med J. 1970 Jul;46(537):425-7. doi: 10.1136/pgmj.46.537.425.
The Uriglox screening test was compared with the modified Griess Nitrite test and with standard urine cultures in the detection of significant bacteriuria on 400 ambulant and asymptomatic residents of the Athens Home for the Aged. The modified Nitrite test alone detected 62%, and the Uriglox test 79% of the 103 cases with positive urine cultures in the examined group. There was significant overlap in the positive cases picked up by each screening test separately, the Uriglox test identifying more infections. Since there were no false-positive cases with either one of the employed tests, the cases identified by one the other both screening tests amounted to 95% of the total number of bacteriuric samples. The combination of the moderately sensitive but highly specific test of Nitrite, with the very sensitive test of Uriglox, can effectively substitute for the expensive and time-consuming quantitative bacterial counts with pour-plate techniques in mass screening for bacteriuria.
在对雅典养老院400名门诊且无症状的老人进行检测时，将Uriglox筛查试验与改良格里斯亚硝酸盐试验及标准尿培养进行比较，以检测显著菌尿。在所检查的组中，103例尿培养阳性病例中，单独改良亚硝酸盐试验检测出62%，Uriglox试验检测出79%。每种筛查试验单独检出的阳性病例有显著重叠，Uriglox试验识别出更多感染病例。由于所采用的两种试验均无假阳性病例，两种筛查试验识别出的病例占菌尿样本总数的95%。亚硝酸盐中度敏感但高度特异的试验与非常敏感的Uriglox试验相结合，可有效替代用倾注平板技术进行的昂贵且耗时的定量细菌计数，用于菌尿的大规模筛查。
