Kubicki S, Azcona A
Acta Anaesthesiol Belg. 1979;30 Suppl:123-33.
Both pentazocine and buprenorphine are hypnoanalgetics of the agonistic-antagonist group. They suppress the inhibitory effect of fentanyl upon the central nervous system. They show also secondary their own inhibitory properties (fig. 8). The agonistic-antagonists can be further divided in excitants (like pentazocine) and non-excitants (buprenorphine).
喷他佐辛和丁丙诺啡均为激动 - 拮抗型催眠镇痛药。它们可抑制芬太尼对中枢神经系统的抑制作用。它们还会继发性地表现出自身的抑制特性(图8)。激动 - 拮抗剂可进一步分为兴奋型(如喷他佐辛)和非兴奋型(丁丙诺啡)。