Kacaki J N, Balduzzi P C, Vaughan J H
Clin Exp Immunol. 1970 Jun;6(6):885-9.
In the literature there are speculations concerning a possible role of Rubella virus in the etiopathogenesis of rheumatoid arthritis (RA). Rubella haemagglutination inhibition (RHI) antibody titres were determined in sera from thirty-six pairs of patients with RA and diseases unrelated to RA, matched for age and sex. Latex flocculation tests (LFT) were performed in both groups, as well. Mean ranks (log) of RHI test for the RA and non-RA groups were almost identical (5·75 and 5·94, respectively). Titre of RHI was unrelated to the presence or absence, or titre, of LFT. Thus, no evidence of continuing Rubella virus infection can be found in patients with RA by this antibody test. The possibility that the aetiology of RA may be related to some viral infection is nevertheless of continuing interest.
文献中存在关于风疹病毒在类风湿性关节炎（RA）病因发病机制中可能作用的推测。测定了36对年龄和性别匹配的RA患者及与RA无关疾病患者血清中的风疹血凝抑制（RHI）抗体滴度。两组均进行了乳胶凝集试验（LFT）。RA组和非RA组RHI试验的平均秩（对数）几乎相同（分别为5.75和5.94）。RHI滴度与LFT的存在与否或滴度无关。因此，通过该抗体检测在RA患者中未发现持续风疹病毒感染的证据。然而，RA的病因可能与某些病毒感染有关这一可能性仍然备受关注。
