• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

麻风病患者淋巴细胞转移试验结果正常。

Normal lymphocyte transfer tests in leprosy.

作者信息

Saha K, Mittal M M

出版信息

Clin Exp Immunol. 1970 Jun;6(6):969-74.

PMID:5477731
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1712813/
Abstract

Lymphocyte transfer tests (intradermal inoculations of 2·5 million of allogenic lymphocytes) were done in five normal persons, five lepromatous leprosy and four tuberculoid leprosy patients. Observations were made daily for at least 10 days. In normal persons an initial reaction of moderate induration and erythema reached its maximum diameter between 24 and 48 hr and a secondary reaction occurred on the 3rd–5th day, reached its peak on the 6th–7th day and disappeared between the 10th and 13th day. In the lepromatous leprosy cases there was neither an initial nor a secondary reaction. In two of four cases of tuberculoid leprosy only an initial reaction was observed while in the other two cases the reaction appeared on the 4th day, reached its peak on the 6th day and persisted to the 13th day.

摘要

对5名正常人、5名瘤型麻风患者和4名结核样型麻风患者进行了淋巴细胞转移试验(皮内接种250万个同种异体淋巴细胞)。每天进行观察,至少观察10天。在正常人中,最初出现中度硬结和红斑反应,在24至48小时之间达到最大直径,第二次反应出现在第3至5天,在第6至7天达到峰值,并在第10至13天消失。在瘤型麻风病例中,既没有最初反应也没有第二次反应。在4例结核样型麻风病例中,2例仅观察到最初反应,而在另外2例中,反应在第4天出现,在第6天达到峰值,并持续到第13天。

相似文献

1
Normal lymphocyte transfer tests in leprosy.麻风病患者淋巴细胞转移试验结果正常。
Clin Exp Immunol. 1970 Jun;6(6):969-74.
2
A study of cell mediated immunity in leprosy: changing trends in the immunological spectrum of the disease.麻风病细胞介导免疫的研究:疾病免疫谱的变化趋势
Clin Exp Immunol. 1971 Jun;8(6):901-9.
3
Transfer of cell-mediated immunity in leprosy by transfer of lymph node cells.通过转移淋巴结细胞实现麻风病细胞介导免疫的转移。
Int J Lepr Other Mycobact Dis. 1974 Jan-Mar;42(1):28-32.
4
Attempts to convert lepromatous into tuberculoid-type leprosy with blood lymphocyte extracts from sensitized donors.尝试用来自致敏供体的血液淋巴细胞提取物将瘤型麻风转化为结核样型麻风。
Clin Exp Immunol. 1973 Sep;15(1):87-92.
5
Applicability of the normal lymphocyte transfer test to the dog.正常淋巴细胞转移试验在犬类中的适用性。
Am Surg. 1968 Jun;34(6):457-60.
6
[Disturbance of the cellular defense in sarcoidosis].[结节病中细胞防御的紊乱]
Med Klin. 1971 Dec 17;66(51):1765-9.
7
[Intracorneal transfer reactions of allogenic lymphocytes].
Ber Zusammenkunft Dtsch Ophthalmol Ges. 1972;71:295-9.
8
[Suggestions on the control and stimulation of cellular immunity in cancer].[关于癌症中细胞免疫控制与刺激的建议]
Chirurg. 1978 Nov;49(11):695-8.
9
Reactions obtained with transferred lymphocytes in patients with advanced cancer.晚期癌症患者中转移淋巴细胞的反应。
J Natl Cancer Inst. 1965 Dec;35(6):927-35.
10
Is the stage set for lymphoid tissue replacement in active lepromatous leprosy patients?活跃性瘤型麻风患者的淋巴组织替代阶段已经就绪了吗?
Lepr India. 1977 Jan;49(1):1-5.

引用本文的文献

1
Attempts to convert lepromatous into tuberculoid-type leprosy with blood lymphocyte extracts from sensitized donors.尝试用来自致敏供体的血液淋巴细胞提取物将瘤型麻风转化为结核样型麻风。
Clin Exp Immunol. 1973 Sep;15(1):87-92.
2
Passive transfer of immunity into leprosy patients by transfusion of lymphocytes and by transfusion of Lawrence's transfer factor.通过淋巴细胞输血和劳伦斯转移因子输血将免疫被动转移至麻风病患者体内。
J Clin Microbiol. 1975 Mar;1(3):279-88. doi: 10.1128/jcm.1.3.279-288.1975.
3
Lymphocyte transformation test in leprosy: decreased lymphocyte reactivity to Mycobacterium leprae in lepromatous leprosy, with no evidence for a generalized impairment.麻风病中的淋巴细胞转化试验:在瘤型麻风中,淋巴细胞对麻风分枝杆菌的反应性降低,无全身性功能损害的证据。
Infect Immun. 1978 Dec;22(3):649-56. doi: 10.1128/iai.22.3.649-656.1978.

本文引用的文献

1
DONOR SELECTION AND COMPATIBILITY TYPING.供体选择与配型
Br Med Bull. 1965 May;21:162-5 PASSIM. doi: 10.1093/oxfordjournals.bmb.a070386.
2
STUDIES OF LYMPHOCYTE TRANSFER REACTIONS IN HODGKIN'S DISEASE.霍奇金病中淋巴细胞转移反应的研究
J Clin Invest. 1965 Apr;44(4):555-64. doi: 10.1172/JCI105168.
3
AN EVALUATION OF THE NORMAL LYMPHOCYTE TRANSFER TEST IN MAN.人体正常淋巴细胞转移试验的评估
J Clin Invest. 1965 Feb;44(2):219-30. doi: 10.1172/JCI105136.
4
Tissue transplantation: a new approach to the "typing" problem.组织移植:解决“分型”问题的新方法。
Br Med J. 1963 Aug 3;2(5352):269-72. doi: 10.1136/bmj.2.5352.269.
5
Normal lymphocyte transfer (NLT) test: negative response in a patient with congenital absence of the thymus.正常淋巴细胞转移(NLT)试验:先天性无胸腺患者的阴性反应。
Transplantation. 1967 May;5(3):555-7.
6
Reactions obtained with transferred lymphocytes in patients with advanced cancer.晚期癌症患者中转移淋巴细胞的反应。
J Natl Cancer Inst. 1965 Dec;35(6):927-35.
7
Lymphocyte transfer tests in cancer patients and healthy people.癌症患者和健康人的淋巴细胞转移试验。
Cancer. 1968 Sep;22(3):500-6. doi: 10.1002/1097-0142(196809)22:3<500::aid-cncr2820220303>3.0.co;2-1.
8
Cellular immunity and the homograft reaction.细胞免疫与同种移植反应。
Br Med Bull. 1967 Jan;23(1):55-60. doi: 10.1093/oxfordjournals.bmb.a070517.
9
Effect of phytohemagglutinin and various mycobacterial antigens on lymphocyte cultures from leprosy patients.植物血凝素和各种分枝杆菌抗原对麻风病患者淋巴细胞培养物的影响。
Proc Soc Exp Biol Med. 1968 Feb;127(2):391-5. doi: 10.3181/00379727-127-32698.
10
Cytotoxic effects in vitro by lymphoid cells from specifically tolerant animals.来自特异性耐受动物的淋巴细胞的体外细胞毒性作用。
Immunology. 1969 Apr;16(4):561-6.