Gilliatt R W, Le Quesne P M, Logue V, Sumner A J
J Neurol Neurosurg Psychiatry. 1970 Oct;33(5):615-24. doi: 10.1136/jnnp.33.5.615.
Nine patients are described with unilateral wasting of the hand muscles associated with elongated C7 transverse processes or with rudimentary cervical ribs. In three patients there was selective wasting of the lateral part of the thenar pad, accompanied by mild weakness of the other hand muscles. In four patients all the hand muscles were wasted, but this was more marked in the lateral part of the thenar pad than elsewhere. In two patients wasting was uniformly distributed throughout the hand. Weakness and wasting in the forearm was only present in four patients and was relatively mild. Sensory loss, when present, affected mainly the inner side of the forearm. Nerve conduction studies revealed no abnormality in the distal part of the median nerve, but some patients had reduced or absent sensory action potentials when the fifth finger was stimulated. In all nine patients a sharp fibrous band was found at operation, which extended from an elongated C7 transverse process or from a rudimentary cervical rib to the region of the scalene tubercle on the first rib. The fibrous band caused angulation of the C8 and T1 roots in five patients, and of the lower trunk of the brachial plexus in three. Pathological changes were frequently visible in affected nerves at the site of angulation. Division of the fibrous band relieved pain and paraesthesiae in eight patients and arrested muscle wasting and weakness in nine patients. There was, however, only slight recovery of power in affected muscles; wasting in the hand appeared to be unchanged after periods of up to eight years.
本文描述了9例手部肌肉单侧萎缩的患者,这些患者伴有C7横突过长或存在颈肋发育不全的情况。3例患者大鱼际垫外侧部分出现选择性萎缩,同时伴有手部其他肌肉轻度无力。4例患者所有手部肌肉均出现萎缩,但大鱼际垫外侧部分的萎缩比其他部位更为明显。2例患者手部萎缩呈均匀分布。仅4例患者出现前臂无力和萎缩,且程度相对较轻。感觉丧失(若存在)主要影响前臂内侧。神经传导研究显示正中神经远端无异常,但部分患者在刺激小指时感觉动作电位降低或消失。在所有9例患者的手术中均发现一条尖锐的纤维带,该纤维带从过长的C7横突或颈肋发育不全处延伸至第一肋斜角肌结节区域。在5例患者中,纤维带导致C8和T1神经根成角,在3例患者中导致臂丛神经下干成角。在成角部位,受影响神经的病理改变常常可见。切断纤维带后,8例患者的疼痛和感觉异常得到缓解,9例患者的肌肉萎缩和无力停止发展。然而,受影响肌肉的力量仅有轻微恢复;长达8年的观察期后,手部萎缩情况似乎没有变化。