Pygott F
Postgrad Med J. 1970 Aug;46(538):505-6. doi: 10.1136/pgmj.46.538.505.
Radiologically demonstrable bone change is found in about one in every six patients with sarcoidosis. The hands and feet are affected and rarely the trunk, an unusual distribution for a disseminate disease. Osteoporosis, cortical thinning and mottled rarefaction are the earliest signs, followed by cystic changes due to the coalescence of adjacent lesions and perhaps pathological fractures. The nasal bones may be directly involved in patients with lupus pernio. Changes in the rest of the skull, in the spine and pelvis are rare and may be bizarre.
在每六例结节病患者中，约有一例可通过放射学检查发现骨骼改变。手部和足部会受到影响，躯干很少受累，这对于一种播散性疾病来说是不寻常的分布。骨质疏松、皮质变薄和斑点状稀疏是最早的体征，随后由于相邻病变融合出现囊性改变，甚至可能发生病理性骨折。冻疮样狼疮患者的鼻骨可能直接受累。颅骨其他部位、脊柱和骨盆的改变很少见，且可能很奇特。
