支气管癌中的内分泌和代谢紊乱
Endocrine and metabolic disordes in bronchial carcinoma.
作者信息
Azzopardi J G, Freeman E, Poole G
出版信息
Br Med J. 1970 Nov 28;4(5734):528-30. doi: 10.1136/bmj.4.5734.528.
Abstract
In an unselected series of 185 patients with histologically confirmed bronchial carcinoma 16 had endocrine disturbances attributable to the tumour (excluding pulmonary osteoarthropathy). Of these, 11 patients had hypercalcaemia; three inappropriate secretion of antidiuretic hormone; one Cushing's disease; three hypertrophic osteoarthropathy; and one gynaecomastia. Cushing's disease and inappropriate antidiuresis are specifically associated with oat-cell tumours, and hypercalcaemia occurs most frequently with squamous carcinoma. A negative correlation exists between gynaecomastia and osteoarthropathy on the one hand and oat-cell carcinoma on the other.
摘要
在一组未经挑选的185例经组织学确诊的支气管癌患者中，16例有归因于肿瘤的内分泌紊乱（不包括肺性肥大性骨关节病）。其中，11例患者有高钙血症；3例有抗利尿激素分泌不当；1例有库欣病；3例有肥大性骨关节病；1例有男子女性型乳房。库欣病和抗利尿激素分泌不当与燕麦细胞癌有特异性关联，高钙血症最常发生于鳞状细胞癌。男子女性型乳房和骨关节病一方面与燕麦细胞癌另一方面之间存在负相关。
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