用抗栓酶进行抗凝用于血液透析

Hall G H, Holman H M, Webster A D

Br Med J. 1970 Dec 5;4(5735):591-3. doi: 10.1136/bmj.4.5735.591.

The defibrinating agent ancrod (Arvin) was used instead of heparin for intermittent haemodialysis. It was an effective, and apparently safe, anticoagulant and reduced the deposition of fibrin and leucocytes on the Cellophane membrane. Administration was more complicated and urea dialysance was less with ancrod than with heparin.

在间歇性血液透析中，使用去纤维蛋白剂安克洛酶（Arvin）替代肝素。它是一种有效的抗凝剂，而且显然是安全的，可减少纤维蛋白和白细胞在赛璐玢膜上的沉积。与肝素相比，安克洛酶的给药更复杂，尿素透析率更低。