Lewis J H
J Chromatogr. 1979 Apr 21;172:295-302. doi: 10.1016/s0021-9673(00)90965-8.
Following the intramuscular administration of nikethamide to a series of greyhounds, both plasma and urine excretion levels were obtained. A qualitative urine screening procedure for both nikethamide and its major metabolite has been devised. The method involves solvent extraction, thin-layer and a two-system gas chromatographic system.