Donaghey C E
J Med Syst. 1979;3(1-2):19-44. doi: 10.1007/BF02225462.
The field of cell kinetics relates to the movement and proliferation of cells through their generative cycle and to how this cycle is affected by chemotherapy treatment. CELLSIM is a discrete, digital simulation language for modeling this process. The language is interpretive, with the interpreter written in FORTRAN. It has been implemented on a wide variety of computer systems. The language features dynamic memory allocation, arithmetic string manipulation, and the capability of generating random variates from a number of probability distributions. The language has continued to evolve as the needs and desires of cancer researchers have been discovered. Its early use was only in experimental environments, but it is now being used to prescribe actual chemotherapy treatments.
细胞动力学领域涉及细胞在其生成周期中的移动和增殖，以及该周期如何受到化疗的影响。CELLSIM是一种用于对这一过程进行建模的离散数字模拟语言。该语言是解释性的，解释器用FORTRAN编写。它已在多种计算机系统上实现。该语言具有动态内存分配、算术字符串操作，以及从多种概率分布生成随机变量的能力。随着癌症研究人员需求的发现，该语言不断发展。它早期仅用于实验环境，但现在正被用于制定实际的化疗方案。
