Scott G B, Kenefick J
Br J Exp Pathol. 1970 Aug;51(4):404-10.
The organisation of thrombi, induced by thrombin, was compared in the femoral arteries and veins of dogs in an attempt to investigate the effect of differences in intraluminal pressure on this process. All thrombi possessed a peripheral zone of fibrin, leucocytes and clumps of platelets but this was much thicker and more compact in arterial than in venous thrombi possibly resulting from the higher pulse pressure in the former type of vessel. Where organisation occurred it was predominantly peripheral or marginal and was obviously much more exuberant in arteries than in veins. Thus the extent of such organisation seemed related directly to the thickness of this peripheral zone which in turn was largely dictated by the pulse pressure in the vessel concerned.
为了研究管腔内压力差异对这一过程的影响，对狗股动脉和静脉中由凝血酶诱导形成的血栓组织进行了比较。所有血栓均有一个由纤维蛋白、白细胞和血小板团块组成的外周区，但动脉血栓中的这个外周区比静脉血栓中的厚得多且更致密，这可能是由于前一种血管类型中较高的脉压所致。在发生机化的部位，机化主要发生在外周或边缘，并且在动脉中明显比在静脉中更活跃。因此，这种机化的程度似乎与这个外周区的厚度直接相关，而外周区的厚度又在很大程度上取决于相关血管中的脉压。
