Kreissig I, Lincoff H
Mod Probl Ophthalmol. 1979;20:154-6.
During a period of seven years out of 900 explant operations done in New York 31 sponges had to be removed. In Bonn during the same period a comparable 27 explants out of 1000 operations had to be removed. Clinical infection occurred as early as one week and as late as seven years after the operation. The infection of the sponge manifested as: fistula, granuloma or a subconjunctival haemorrhagic mass. 2/3 of the infections were due to staphylococcus epidermis which acts as a pathogen in the presence of a foreign body. Bonn's requirement of a sterile conjunctiva preoperatively and the use of prophylactic antibiotics postoperatively did not significantly reduce the rate of infection.
在纽约进行的900次植入物取出手术中,有7年时间里必须取出31块海绵。同期在波恩,1000次手术中有27次进行了类似的取出操作。临床感染最早在术后一周出现,最晚在术后七年出现。海绵感染表现为:瘘管、肉芽肿或结膜下出血性肿块。三分之二的感染是由表皮葡萄球菌引起的,在有异物存在的情况下它作为病原体起作用。波恩术前对结膜无菌的要求以及术后使用预防性抗生素并没有显著降低感染率。