肝硬化和非肝硬化住院人群中触珠蛋白0-0表型的评估

Evaluation of haptoglobin phenotype 0-0 in cirrhotic and non-cirrhotic hospital populations.

作者信息

Nandi M, Lewis G P, Jick H, Slone D, Shapiro S, Siskind V

出版信息

J Clin Pathol. 1970 Nov;23(8):695-9. doi: 10.1136/jcp.23.8.695.

DOI:10.1136/jcp.23.8.695

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476870/

Abstract

The haptoglobin phenotypes of 3,332 individuals, consisting of 2,930 caucasians and 402 negroes living in the greater Boston area, were determined. Of these, 3,222 were hospitalized medical patients fully documented regarding diagnoses. One hundred and twentyeight of the total population studied were shown to exhibit starch gel anhaptoglobinaemia (3.7%). Re-evaluation on acrylamide gel of 118 0-0 samples revealed that the majority (94%) were derived from patients exhibiting hypohaptoglobinaemia rather than anhaptoglobinaemia.

摘要

对居住在大波士顿地区的3332人（其中包括2930名白种人和402名黑人）的触珠蛋白表型进行了测定。其中，3222人是住院患者，诊断记录完整。在整个研究人群中，有128人被发现表现出淀粉凝胶无触珠蛋白血症（3.7%）。对118份0-0样本进行丙烯酰胺凝胶再评估发现，大多数（94%）样本来自表现为低触珠蛋白血症而非无触珠蛋白血症的患者。

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引用本文的文献

1

Thin-layer acrylamide gel electrophoresis.薄层丙烯酰胺凝胶电泳

J Clin Pathol. 1970 Nov;23(8):727-9. doi: 10.1136/jcp.23.8.727.

2

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Humangenetik. 1975 Jun 19;28(2):139-46. doi: 10.1007/BF00735746.

本文引用的文献

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SERUM HAPTOGLOBINS IN HAEMOLYTIC STATES.溶血性状态下的血清触珠蛋白

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VARIATIONS IN HETEROZYGOUS EXPRESSION AT THE HAPTOGLOBIN LOCUS.触珠蛋白基因座杂合子表达的变异

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Control gene mutation as a possible explanation of certain haptoglobin phenotypes.将控制基因突变作为某些触珠蛋白表型的一种可能解释。

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Am J Hum Genet. 1962 Jun;14(2):210-9.

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The haptoglobin content of serum in haemolytic anaemia.溶血性贫血患者血清中的触珠蛋白含量。

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Haptoglobin types in American Negroes.美国黑人中的触珠蛋白类型。

Nature. 1959 Jan 17;183(4655):192-3. doi: 10.1038/183192a0.

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Atypical segregation of haptoglobin types in man.人类触珠蛋白类型的非典型分离。

Nature. 1958 Nov 8;182(4645):1324-5. doi: 10.1038/1821324b0.

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