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Reaction rates and biological action of N-methyl- and N-ethyl-N-nitrosourea.

作者信息

Velemínský J, Osterman-Golkar S, Ehrenberg L

出版信息

Mutat Res. 1970 Sep;10(3):169-74. doi: 10.1016/0027-5107(70)90113-2.

DOI:10.1016/0027-5107(70)90113-2
PMID:5489967
Abstract
摘要

相似文献

1
Reaction rates and biological action of N-methyl- and N-ethyl-N-nitrosourea.N-甲基-和N-乙基-N-亚硝基脲的反应速率及生物学作用
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The mutagenic effect of N-nitrosomethylurea on the dumpy locus in Drosophila melanogaster.N-亚硝基甲基脲对黑腹果蝇短粗基因座的诱变作用。
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Forward mutation studies with N-nitroso-N-methyl-urethane and N-nitroso-N-ethylurethane in Schizosaccharomyces pombe.
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4
Induction of mitotic gene conversion by mutagens.诱变剂诱导有丝分裂基因转换
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Induction of mitotic gene conversion with nitrous acid, 1-methyl-3-nitro-1-nitrosoguanidine and other alkylating agents in Saccharomyces cerevisiae.亚硝酸、1-甲基-3-硝基-1-亚硝基胍及其他烷化剂在酿酒酵母中诱导有丝分裂基因转换
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Inactivation and mutation of coliphage T2 by N-methyl-and N-ethyl-N-nitrosourea.用N-甲基-N-亚硝基脲和N-乙基-N-亚硝基脲使大肠杆菌噬菌体T2失活和发生突变。
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Comparison of the mutagenic activity of N-methylnitrosourea, N, N'-dimethylnitrosourea, and N,N', N'-trimethylnitrosourea.
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引用本文的文献

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Chemical mutagenesis: a new strategy against the global threat of infectious diseases.化学诱变:对抗传染病全球威胁的新策略。
Mamm Genome. 2008 May;19(5):309-17. doi: 10.1007/s00335-008-9114-0. Epub 2008 Jun 17.
2
Comparison of alkylation rates and mutagenicity of directly acting industrial and laboratory chemicals: epoxides, glycidyl ethers, methylating and ethylating agents, halogenated hydrocarbons, hydrazine derivatives, aldehydes, thiuram and dithiocarbamate derivatives.直接作用的工业化学品和实验室化学品的烷基化速率与致突变性比较:环氧化物、缩水甘油醚、甲基化和乙基化试剂、卤代烃、肼衍生物、醛、秋兰姆和二硫代氨基甲酸盐衍生物。
Arch Toxicol. 1980 Dec;46(3-4):277-85. doi: 10.1007/BF00310445.
3
Bone marrow genotoxicity of N-methyl, N-nitrosourea (NMU): n-alkanols as sister chromatid exchange (SCE) anti-inducers.
Experientia. 1983 Jul 15;39(7):757-9. doi: 10.1007/BF01990311.
4
Alkylation of deoxyribonucleic acid by carcinogens dimethyl sulphate, ethyl methanesulphonate, N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea. Relative reactivity of the phosphodiester site thymidylyl(3'-5')thymidine.致癌物硫酸二甲酯、甲磺酸乙酯、N-乙基-N-亚硝基脲和N-甲基-N-亚硝基脲对脱氧核糖核酸的烷基化作用。磷酸二酯位点胸苷酰(3'-5')胸苷的相对反应活性。
Biochem J. 1978 Jun 1;171(3):575-87. doi: 10.1042/bj1710575.
5
Isolation and identification of products from alkylation of nucleic acids: ethyl- and isopropyl-purines.核酸烷基化产物的分离与鉴定:乙基嘌呤和异丙基嘌呤
Biochem J. 1975 Jan;145(1):73-84. doi: 10.1042/bj1450073.