[苏联LTF - 130癣病疫苗的比较免疫学研究及动物流行病学效果测定]

[Comparative immunological studies and the determination of the epizootiological effectiveness of Soviet vaccine LTF-130 in trichophytosis].

作者信息

Stankushev Kh, Duparinova M, Kostov G, Gradinarski I

出版信息

Vet Med Nauki. 1979;16(10):67-73.

Abstract

The immunological response of calves vaccinated against herpes is explained and the epizootic effectiveness of the Soviet vaccine ltf 130 applied in Bulgaria is assessed. The antigenic relation of the vaccine's strain with the agent causing herpes in Bulgaria was revealed by parallel investigation on serum RCB of calves suffering from herpes and of calves vaccinated with ltf 130. The immunological response was assessed by proving the existence of complement binding antibodies. It was found that vaccinated calves react by producing complement binding antibodies up to the 45th day post immunization. During the 1976-1978 year period 62 121 calves and heifers were treated for medicative purposes and 653 666 calves and heifers--for prophylactic purposes. From all vaccine treated animals 95.4-98.8% recovered. No cases of herpes were observed in animals vaccinated prophylactically.

摘要

本文解释了接种抗疱疹疫苗的犊牛的免疫反应，并评估了苏联ltf 130疫苗在保加利亚应用的 epizootic 效果。通过对患有疱疹的犊牛和接种ltf 130疫苗的犊牛的血清RCB进行平行调查，揭示了疫苗株与保加利亚引起疱疹的病原体之间的抗原关系。通过证明补体结合抗体的存在来评估免疫反应。发现接种疫苗的犊牛在免疫后第45天之前通过产生补体结合抗体做出反应。在1976 - 1978年期间，62121头犊牛和小母牛接受了药物治疗，653666头犊牛和小母牛接受了预防性治疗。在所有接受疫苗治疗的动物中，95.4 - 98.8%康复。在接受预防性接种的动物中未观察到疱疹病例。