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[原发性淋巴结浆细胞瘤的诊断与鉴别诊断]

[Diagnosis and differential diagnosis of primary lymph node plasmacytomas].

作者信息

Wessel H, Stenzel L, Kujat G

出版信息

Z Gesamte Inn Med. 1979 Nov 15;34(22):676-80.

PMID:549301
Abstract

A case of 75 year-old man is reported, who died of a tuberculous leptomeningomyeloencephalitis complicating a generalized primary lymph node plasmacytoma. The malignant lymphoma has been diagnosed in a lymph node biopsy from the right supraclavicular region seven years before the death and was treated with cytostatics over a period of four and a half months. Autopsy revealed the neoplastic involvement of supraclavicular and axillary lymph nodes, tumour infiltration of the sternum and diffuse neoplastic plasmacytosis of the bone marrow. The lymph node plasmacytoma has to be differentiated from reactive lymph node plasmacytosis, angioimmunoblastic lymphadenopathy with excessive plasmacytosis, lymphoplasmacytic immunocytoma, metastasis of an extramedullary plasmacytoma or of a multiple myeloma, and from a lymph node involved by plasma-cell leukemia.

摘要

报告了一例75岁男性病例,该患者死于结核性软脑膜脊髓脑炎,并发全身性原发性淋巴结浆细胞瘤。恶性淋巴瘤在死亡前七年经右锁骨上区淋巴结活检确诊,并接受了四个半月的细胞抑制剂治疗。尸检发现锁骨上和腋窝淋巴结有肿瘤累及,胸骨有肿瘤浸润,骨髓有弥漫性肿瘤性浆细胞增多。淋巴结浆细胞瘤必须与反应性淋巴结浆细胞增多、伴有过多浆细胞增多的血管免疫母细胞性淋巴结病、淋巴浆细胞性免疫细胞瘤、髓外浆细胞瘤或多发性骨髓瘤的转移以及浆细胞白血病累及的淋巴结相鉴别。

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