Lorenz G, Bärenwald G
Acta Hepatogastroenterol (Stuttg). 1979 Dec;26(6):435-8.
The results of 99 histologically examined liver biopsy samples--14 of them also examined under the electron microscope--taken from 68 insulin-treated diabetic children of both sexes at an age from 2-14 years. most of them with long-standing diabetes, are presented, thus giving a survey of morphologic liver findings of diabetes mellitus in this age group. Apart from metabolic changes, such as amount of fat and glycogen storage--including the nuclear glycogen of the liver--secondary diseases of inflammatory nature were found to play a prominent role in one third of the children. There are definite correlations with the degree of metabolic decompensation, demanding preventive and therapeutic measures.
对68名年龄在2至14岁的接受胰岛素治疗的糖尿病患儿（男女均有）进行了99次肝脏活检样本的组织学检查，其中14份样本还进行了电子显微镜检查。他们大多数患有长期糖尿病，现将检查结果呈现出来，从而对该年龄组糖尿病患者的肝脏形态学表现进行概述。除了代谢变化，如脂肪和糖原储存量（包括肝脏核内糖原）外，发现三分之一的患儿中具有炎症性质的继发性疾病起了显著作用。这些与代谢失代偿程度存在明确的相关性，需要采取预防和治疗措施。
